No, Aase syndrome does not go away on its own, but the anemia it causes often improves as a child gets older.
Aase syndrome is present from birth and comes from a genetic change that affects how bone marrow makes red blood cells and how some bones form. The anemia is usually most noticeable in infancy, and many children improve over the first few years, sometimes enough to stop transfusions or lower steroid doses. Bone and joint differences such as thumbs with an extra bone stay unless they are treated directly. Regular blood counts, iron checks when transfusions are used, and steady follow-up with a hematologist are what keep things stable. Ask the specialist before changing or stopping any treatment, since dose changes need monitoring.
How Aase syndrome is managed
Common questions
Can Aase syndrome go away on its own?
No. Aase syndrome is caused by a change in the genes that guide bone marrow and bone development, and that underlying change stays for life. What can change is the anemia. Many children need red blood cell transfusions in the first year, then respond to corticosteroids, and some see bone marrow function improve enough that treatment can be reduced under close monitoring. Skeletal features such as triphalangeal thumbs, narrow shoulders, or cleft palate do not correct themselves and are managed with surgery or therapy when they limit function. A hematologist and a geneticist should guide care and track blood counts over time.