Can ABO incompatibility go away on its own?
Last updated September 6, 2026.
**ABO blood type differences do not go away, but mild effects in your newborn can resolve without treatment.** During pregnancy, your antibodies can cross the placenta and break down your baby's red blood cells, causing jaundice or anemia. These antibodies gradually clear after birth, but your baby's bilirubin level and blood count determine whether treatment is needed. Your clinician may recommend monitoring, special light treatment called phototherapy, or treatment for anemia. Feed your baby regularly and keep every recommended follow-up appointment. If you mean an ABO reaction from a blood transfusion, you need immediate medical care.
What to do
- **Keep scheduled checks:** Follow your baby's clinician's plan for bilirubin testing and any blood count checks.
- **Feed regularly:** Offer frequent feeds and ask your care team for help if your baby struggles to feed.
- **Use prescribed treatment:** Follow phototherapy instructions and do not use sunlight to treat jaundice.
- **Get urgent assessment:** Seek urgent care if your baby develops jaundice in the first 24 hours or feeds poorly.
- **Recognize an emergency:** Get emergency care if your baby cannot be woken or has trouble breathing.
- **Report transfusion symptoms:** Tell your medical team immediately about fever, chills, back pain, or breathing trouble during or after a transfusion.
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