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Short answer Alcohol and amoxapine: what to know Common questions Related questions Sources**No, you should avoid alcohol while taking amoxapine.**
Alcohol increases amoxapine's sedative effects and can make drowsiness, slowed breathing, and poor coordination worse. Alcohol also raises seizure risk and can reduce antidepressant benefit. Combining alcohol with other sedatives or opioids adds danger. Talk with your prescriber before drinking and do not drive or operate machinery after drinking while on this medicine.
Alcohol and amoxapine: what to know
Common questions
Can you drink alcohol while taking Amoxapine?
Do not drink alcohol while taking amoxapine. Alcohol amplifies the drug's central nervous system depression and can increase drowsiness, slowed breathing, impaired coordination, falls, and seizure risk. Alcohol can also blunt antidepressant response and interact with other sedating medicines. Tell your clinician if you have a seizure disorder or heavy alcohol use before starting amoxapine. Avoid driving or heavy machinery until you know how the combination affects you and seek care for severe drowsiness or any seizure.