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Can you drink alcohol while taking Amphotericin B Injection?

Updated Sep 8, 20261 min readAnswer
On this pageShort answer Alcohol and amphotericin B: the rules Common questions Related questions Sources
Short answer

**It depends: moderate alcohol is not universally banned, but alcohol can increase kidney or liver stress while you receive amphotericin B.**

Amphotericin B is given by IV and commonly affects kidneys, electrolytes, and occasionally liver tests. Alcohol, especially heavy or binge drinking, can dehydrate you and add extra stress to kidneys and liver, raising risk of harm. You should avoid alcohol on infusion days and while side effects or abnormal labs are being evaluated. Talk with the clinician who prescribed the drug for advice tailored to your kidney, liver, and other medications.

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Alcohol and amphotericin B: the rules

1**Ask your clinician:**Tell them if you drink alcohol or have known kidney or liver disease.
2**Avoid alcohol on infusion days:**Do not drink on days you receive an amphotericin B infusion or while side effects are being assessed.
3**Stay hydrated:**Drink fluids unless your clinician says otherwise to help reduce kidney stress.
4**Avoid other nephrotoxins:**Do not take NSAIDs or other kidney-harming drugs without checking with your provider.
5**Get lab checks:**Have kidney and liver tests as recommended and report new symptoms like dark urine or dizziness.

Common questions

Can you drink alcohol while taking Amphotericin B Injection?

Amphotericin B does not carry a blanket prohibition on moderate alcohol in product information, but it is a powerful IV antifungal that commonly affects kidney function and can alter electrolytes and sometimes liver tests. Alcohol, particularly heavy or repeated drinking, can dehydrate you and increase stress on both kidneys and liver, which can raise the chance of kidney injury or worsen side effects. Avoid alcohol on days you receive infusions and while labs or symptoms are being checked, do not combine alcohol with other liver-harming or kidney-harming drugs, stay well hydrated unless told otherwise, and ask your prescribing clinician for specific guidance and lab monitoring if you drink alcohol regularly or have liver or kidney disease.

About this page. Written and maintained by the Pymander Health team. Last updated September 8, 2026.

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