Can you drink alcohol while taking Anakinra?
Last updated September 7, 2026.
**Anakinra has no listed direct interaction with alcohol, but whether you can drink depends on your health and other medicines.** The prescribing information for anakinra, sold as Kineret, does not establish a safe alcohol limit during treatment. Ask your prescriber about drinking if you have liver disease, abnormal liver tests, or take other medicines. If you also take methotrexate, avoid alcohol because it increases the risk of liver damage. Drinking less reduces alcohol related health risks, and you should not skip anakinra doses to drink.
What to do
- **Check your medicines:** Ask your pharmacist to review your prescriptions, nonprescription medicines, and supplements for alcohol interactions.
- **Avoid alcohol with methotrexate:** If you also take methotrexate, avoid drinking because alcohol increases its risk of liver damage.
- **Review your liver health:** Discuss alcohol with your prescriber before drinking if you have liver disease or abnormal liver tests.
- **Choose less alcohol:** If your clinician says drinking is appropriate, keep your intake low and avoid binge drinking.
- **Keep your dosing schedule:** Do not skip or delay anakinra doses to make room for drinking.
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