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Can you take Adalimumab Injection while pregnant?

Updated Sep 7, 20262 min readAnswer
On this pageShort answer Taking Adalimumab Injection while pregnant: what to do Common questions Related questions Sources
Short answer

In most cases yes, adalimumab can be used during pregnancy, and many people stay on it because keeping the underlying disease controlled protects both you and your baby.

Adalimumab is an antibody that crosses the placenta mainly in the second and third trimesters, so a baby exposed late in pregnancy can carry the drug for several months after birth. That matters most for live vaccines, which are usually delayed until the baby is at least 6 months old. Some specialists adjust the timing of the last dose before delivery, especially if your disease has been quiet, while others continue treatment straight through. Flares of rheumatoid arthritis, Crohn disease, ulcerative colitis, or psoriasis during pregnancy are linked to problems of their own, so stopping is not automatically the safer choice. Your rheumatologist, gastroenterologist, or obstetrician should make this plan with you, ideally before you conceive.

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Taking Adalimumab Injection while pregnant: what to do

1Plan before you conceive:Ask your specialist how they want to handle adalimumab during pregnancy while you are still planning, not after a positive test.
2Do not stop on your own:Skipping doses without a plan can trigger a flare that is harder on the pregnancy than staying on treatment.
3Tell every clinician:Make sure your obstetrician, specialist, and your baby's pediatrician all know you used adalimumab and when your last dose was.
4Time infant vaccines:Live vaccines such as rotavirus and BCG are usually postponed until your baby is at least 6 months old; inactivated vaccines follow the normal schedule.
5Ask about breastfeeding:Adalimumab passes into breast milk in very small amounts and is generally considered compatible with nursing, so raise it rather than assuming you must stop.
6Report the exposure:Ask about enrolling in a pregnancy exposure registry, which tracks outcomes and improves guidance for future pregnancies.

Common questions

Can you take Adalimumab Injection while pregnant?

Adalimumab is often continued during pregnancy when you need it to keep inflammatory arthritis, psoriasis, or inflammatory bowel disease under control, because a flare carries its own risks for you and the pregnancy. It is an antibody that crosses the placenta most in the second and third trimesters, so your baby can have measurable drug levels for several months after birth. Tell your baby's doctor about the exposure and delay live vaccines such as rotavirus and BCG until at least 6 months of age unless the pediatrician advises otherwise. Do not stop or restart adalimumab on your own; your rheumatologist, gastroenterologist, or obstetrician should guide that decision.

About this page. Written and maintained by the Pymander Health team. Last updated September 7, 2026.

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