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Can you take Amisulpride Injection while pregnant?

Updated Sep 7, 20262 min readAnswer
On this pageShort answer Pregnancy and amisulpride injection: what to know Common questions Related questions Sources
Short answer

There is not enough human data to call amisulpride injection safe in pregnancy, so it is used only when your surgical and anesthesia team judges the benefit worth the unknowns.

Amisulpride injection is sold in the US as Barhemsys and is given by IV to prevent or treat nausea and vomiting after surgery. The FDA label does not establish that it is safe for a developing baby, because human pregnancy experience with it is limited. Since it is given once in a hospital or surgery center, this is a decision made with your care team rather than something you manage at home. Tell every member of that team you are pregnant or could be, and hand over your full medicine list, since amisulpride can affect heart rhythm when combined with other drugs that prolong the QT interval.

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Pregnancy and amisulpride injection: what to know

1Say you are pregnant early:Tell your surgeon, anesthesia team, and preop nurse before the procedure, including if pregnancy is only possible.
2Know the setting:Amisulpride injection is given by IV in a hospital or surgery center and is not dispensed for use at home.
3Ask about alternatives:Ask whether an antiemetic with more pregnancy experience fits your surgery and your history.
4Share every medicine:List prescriptions, supplements, and over the counter products, since amisulpride can add to QT prolongation from other drugs.
5Do not confuse the products:Oral amisulpride tablets sold outside the US are a daily antipsychotic and need a separate talk with your prescriber.
6Loop in your obstetric clinician:Any surgery during pregnancy deserves a conversation about timing, monitoring, and postoperative care.

Common questions

Can you take Amisulpride Injection while pregnant?

Amisulpride injection, sold in the US as Barhemsys, is a one dose IV medicine used to prevent or treat nausea and vomiting after surgery. It is not a prescription you fill or take at home, so the choice is made by your anesthesia and surgical team on the day. Human data in pregnancy is limited and the label does not establish safety, so it is used only when the expected benefit outweighs what is unknown. Tell every clinician you are pregnant or might be before any procedure. Antiemetics with more pregnancy experience, such as ondansetron or metoclopramide, may be considered first, and your obstetric clinician can weigh in on timing and anesthesia choices.

About this page. Written and maintained by the Pymander Health team. Last updated September 7, 2026.

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