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Short answer Pregnancy and anifrolumab: what to know Common questions Related questions Sources**Taking anifrolumab-fnia (Saphnelo) while pregnant requires an individual decision with your lupus specialist because its pregnancy safety is not established.**
Human pregnancy data are too limited to determine whether this medicine increases the risk of birth defects or miscarriage. Your baby’s exposure may be greater in the third trimester because antibodies cross the placenta as pregnancy progresses. Your clinician must also consider the pregnancy risks of active lupus when reviewing treatment options. Tell your lupus specialist and pregnancy care clinician if you are pregnant or planning pregnancy, and get advice before changing your treatment.
Pregnancy and anifrolumab: what to know
Common questions
Can you take Anifrolumab-fnia Injection while pregnant?
Anifrolumab-fnia (Saphnelo) has not been established as safe during pregnancy. Human data are too limited to determine its effects on birth defects, miscarriage, or other pregnancy outcomes. Your lupus specialist and pregnancy care clinician need to weigh these unknowns against the risks of active lupus and consider other treatments. If you become pregnant while receiving it, contact your prescriber promptly, ideally before your next dose. Do not stop or change your lupus medicines on your own. Ask about the pregnancy exposure registry if you have used Saphnelo during pregnancy.