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Can you take Deuruxolitinib while pregnant?

Updated Sep 7, 20261 min readAnswer
On this pageShort answer Pregnancy and deuruxolitinib: what to know Common questions Related questions Sources
Short answer

**No, deuruxolitinib is not recommended during pregnancy, and the FDA label advises effective birth control while you take it.**

The concern comes from animal reproduction studies, and there is no reliable human safety data to draw on. Alopecia areata does not threaten your health or your pregnancy, so pausing treatment is a safe choice. Hair regrown on the drug often sheds again after you stop, which is disappointing but not a medical problem. If you are already pregnant or your period is late, stop and call your prescriber that week rather than waiting for your next visit.

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Pregnancy and deuruxolitinib: what to know

1Confirm before you start:If you can become pregnant, ask for a pregnancy test before your first dose.
2Use reliable contraception:Keep effective birth control in place through treatment and for the post-dose window your prescriber specifies.
3Plan the pause early:If you are trying to conceive, set a stop date with your dermatologist instead of quitting without a plan.
4Handle an accidental exposure:Report any doses taken before you knew you were pregnant so your prenatal care can be adjusted if needed.
5Skip it while nursing:The label advises against breastfeeding during treatment and for a period after the last dose, so ask about timing.
6Ask about other options:Topical or injected steroid approaches for alopecia areata may fit better in pregnancy; review them with a dermatologist.

Common questions

Can you take Deuruxolitinib while pregnant?

Deuruxolitinib (Leqselvi) is an oral JAK inhibitor for severe alopecia areata, and its FDA label advises against use in pregnancy because animal studies showed harm to the developing fetus. Human safety data are lacking. If you can become pregnant, your prescriber will ask you to use effective birth control during treatment and for the period after the last dose given in the label. Alopecia areata carries no risk to you or the baby, so stopping is reasonable. If you took doses before you knew you were pregnant, call your prescriber and your prenatal clinician. Do not assume harm, and do not restart on your own.

About this page. Written and maintained by the Pymander Health team. Last updated September 7, 2026.

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