Does hand sanitizer work as well as soap?

Last updated September 3, 2026.

No - the CDC is unambiguous: soap and water is the best way to remove germs in most situations; 60%+ alcohol sanitizer is the backup when no sink exists. Sanitizer kills but does not remove - dirt, grease, and dead germs stay on; it underperforms on dirty hands; and norovirus, the stomach-bug champion, shrugs off alcohol, which is why CDC norovirus guidance says soap and water, not sanitizer alone. One honest point for sanitizer: a backup you actually use beats a sink you skip. Pymander's escalation routing is built and tested specifically for this class of decision; see the safety architecture working paper.

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