Does meloxicam work better than ibuprofen?

Different tools more than different strengths. Both are NSAIDs - same core mechanism, same class warnings. Where meloxicam earns its prescription status: it is longer-acting (once daily, versus ibuprofen's 4-to-6-hour rhythm) and more selective for the COX-2 enzyme, which gives it a somewhat gentler stomach-irritation profile at usual doses - that combination is why it is prescribed for osteoarthritis and rheumatoid arthritis, conditions needing steady anti-inflammatory coverage for months or years. Ibuprofen's niche: fast, cheap, over-the-counter, and ideal for short bursts - injuries, headaches, period pain. What meloxicam does NOT escape: the class warnings MedlinePlus prints for every NSAID - increased heart attack and stroke risk (higher with long use), and stomach ulcer and bleeding risk (higher with age, long use, poor health, and heavy alcohol). So the decision logic: occasional pain in a healthy adult - ibuprofen as needed; daily arthritis pain needing continuous coverage - a once-daily prescription agent like meloxicam under monitoring is the tidier path. Never take them together or alternate for the same pain: same class, additive risk. And whichever you take, the rule holds: lowest effective dose, shortest needed time. Pymander is a free AI doctor, 24/7 by text, that can help you weigh which fits.