**Alkaptonuria is an inherited condition that lasts your whole life.**
If you have alkaptonuria, it is present from birth, even if you do not notice symptoms until adulthood. A substance called homogentisic acid builds up over time, causing dark urine and eventually affecting cartilage and joints. Your symptoms and how quickly they progress vary, but appropriate medical care generally allows a normal life expectancy. Regular follow-up and a physical therapy plan can help you manage pain and maintain movement.
How alkaptonuria is managed
Common questions
How long does Alkaptonuria last?
Alkaptonuria lasts your whole life because it results from an inherited gene change. It does not go away on its own, and there is currently no cure. You may notice urine that darkens after standing from infancy, while joint pain and stiffness often develop in adulthood. Symptoms can progress as homogentisic acid builds up in tissues. Treatment helps manage symptoms, and life expectancy is generally normal with appropriate care. Ask your clinician about physical therapy, pain relief, and monitoring your joints, heart valves, and kidneys.