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Short answer How long Amisulpride Injection stays in your system Common questions Related questions Sources**Amisulpride injection, sold in the US as Barhemsys, has an elimination half-life of about 4 to 5 hours, so most people clear nearly all of it within about a day of the dose.**
The exact timing depends on your kidney function, because amisulpride leaves the body mostly through urine and largely unchanged. With severe kidney impairment the drug lingers longer, which is why the label advises against using it in that setting. A second dose during the same surgical day can stretch the window a little further. Drowsiness or a mild drop in blood pressure usually settles within hours, well before the drug is fully gone. If you notice restlessness, muscle stiffness, or spasms after a dose, contact a clinician.
How long Amisulpride Injection stays in your system
Common questions
How long does Amisulpride Injection stay in your system?
Amisulpride injection, used in the US as Barhemsys for nausea and vomiting around surgery, has an elimination half-life of roughly 4 to 5 hours. Blood levels fall by about half each half-life, so after four or five of them, close to one day, very little remains. Your kidneys do most of the clearing, so reduced kidney function slows the process and your anesthesia team may avoid repeat dosing. The antinausea effect fades sooner than full clearance. Amisulpride is not included in standard workplace drug panels. Tell your care team about kidney disease, heart rhythm problems, low potassium, or other medicines before you receive a dose.