On this page
Short answer What to expect from an amisulpride injection Common questions Related questions Sources**Amisulpride injection works quickly: it goes straight into a vein, and relief from nausea is usually noticeable within about 30 minutes.**
In the US, amisulpride injection is sold as Barhemsys and is used only to prevent or treat nausea and vomiting after surgery. Because it is given intravenously over 1 to 2 minutes, drug levels peak almost immediately rather than building up over days. Timing feels different depending on the situation: a dose given at the start of anesthesia is meant to keep nausea from starting, while a dose given in recovery is judged by how you feel over the next hour. Anesthesia, opioid pain medicine, and motion during transport can all keep nausea going even after the drug is on board. This injection is not the same as oral amisulpride used outside the US as an antipsychotic, which takes weeks to show its full effect.
What to expect from an amisulpride injection
Common questions
How long does Amisulpride Injection take to work?
Amisulpride injection is the IV antiemetic Barhemsys, used to prevent or treat nausea and vomiting after surgery. It is given into a vein over 1 to 2 minutes, so blood levels peak right away and the anti-nausea effect usually begins within about 30 minutes. For prevention, a 10 mg dose is given around the start of anesthesia. For nausea that has already started, a 10 mg dose is given after surgery, and repeat dosing is not recommended. If you still feel sick an hour after the dose, tell your nurse or anesthesia team, since a drug from a different class often works better than a second dose of the same one.
