Is Anacaulase-bcdb topical addictive?
Last updated September 7, 2026.
**No, anacaulase-bcdb topical is not known to be addictive.** You receive this medicine, sold as NexoBrid, to remove dead tissue from certain deep burns caused by heat. It contains enzymes from pineapple stems, and your healthcare team applies and removes the gel during a supervised procedure. You also receive separate medicines for pain, so ask your clinician about their individual addiction risks. Share your medication list, allergy history, and any history of substance use problems before treatment.
What to do
- **Ask about pain medicines:** Have your clinician explain which medicines you will receive and their addiction risks.
- **Share your history:** Tell your care team about any past substance use problems before treatment.
- **Review your medicines:** Give your clinician a list of your prescriptions, supplements, and nonprescription medicines.
- **Mention allergies:** Tell your team if you are allergic to pineapple, papaya, bromelain, or papain.
- **Report bleeding risks:** Tell your clinician about bleeding disorders or blood thinner use before the procedure.
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