How it worksSafetyHealth libraryOur mission Sign in Start a free consult
Pymander
Free consult

What are the side effects of Adalimumab Injection?

Updated Sep 7, 20261 min readAnswer
On this pageShort answer Living with adalimumab: what to watch for Common questions Related questions Sources
Short answer

**Adalimumab injections can cause pain or redness where you inject, headaches, nausea, and an increased risk of infections.**

You may have mild symptoms, but infections can become serious because adalimumab reduces your ability to fight them. Your medical history and other medicines that suppress your immune system affect your risk. Less common serious problems include severe allergic reactions, liver or nerve problems, worsening heart failure, and certain cancers. Rotate injection sites and contact your prescriber about symptoms that worsen or do not go away.

What are the side effects of Adalimumab Injection? Ask our AI doctor - a straight answer in plain language, free, 24/7. Start a free consult Free · Private · 24/7
Find answers about adalimumab injectionStart a free AI doctor consult

Living with adalimumab: what to watch for

1**Rotate injection sites:**Use a different spot each time and avoid skin that is sore, bruised, red, or hard.
2**Report persistent symptoms:**Contact your prescriber if headaches, nausea, or injection reactions bother you or do not go away.
3**Watch for infection:**Call your prescriber promptly for fever, a persistent cough, or painful urination.
4**Get emergency help:**Call 911 if you have trouble breathing or swelling of your face or throat.
5**Review your medicines:**Tell your care team about all your medicines and check with them before receiving vaccines.

Common questions

What are the side effects of Adalimumab Injection?

Adalimumab can cause injection site redness, itching, pain, or swelling, plus headaches, nausea, and infections. It reduces your ability to fight infections, including tuberculosis. Less common serious risks include allergic reactions, liver or nerve problems, worsening heart failure, and certain cancers. Call your prescriber promptly if you develop fever, a persistent cough, painful urination, unusual bruising, or yellow skin or eyes. Call 911 for trouble breathing or swelling of your face or throat. Rotate injection sites and report reactions that worsen or persist.

About this page. Written and maintained by the Pymander Health team. Last updated September 7, 2026.

Questions about this?Start a free consult