What are the side effects of Afamitresgene Autoleucel Injection?
Last updated September 7, 2026.
**Afamitresgene autoleucel (Tecelra) can cause nausea, fatigue, fever, bowel changes, and serious immune reactions or infections.** Your side effects can reflect both the infusion and the chemotherapy given beforehand. Low blood counts can persist for weeks, increasing your risk of infection, bleeding, or tiredness. Cytokine release syndrome is an immune reaction that needs immediate treatment, and confusion or trouble speaking also needs urgent evaluation. Keep your blood test appointments and ask your cancer care team how to manage nausea and changes in appetite.
What to do
- **Report symptoms promptly:** Contact your cancer care team immediately for fever, chills, dizziness, or a fast heartbeat.
- **Get emergency help:** Call 911 for severe trouble breathing, a seizure, or loss of consciousness.
- **Keep monitoring appointments:** Attend scheduled visits and blood tests to check your blood counts and recovery.
- **Manage nausea with guidance:** Ask your treatment team which nausea medicines and fluid intake are right for you.
- **Pause driving:** Avoid driving or operating dangerous machinery for at least 2 weeks after your infusion.
- **Plan ongoing follow-up:** Keep long-term cancer follow-up because secondary cancers are a possible risk.
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