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Short answer Living with amoxapine: what to watch for Common questions Related questions SourcesThe most common amoxapine side effects are drowsiness, dry mouth, constipation, blurred vision, dizziness when you stand up, and weight gain, and a smaller number of people develop movement problems such as tremor, stiffness, or restlessness.
Amoxapine is a tricyclic-type antidepressant that also blocks dopamine, which is why it can cause movement effects that most other antidepressants do not. Many of the routine effects fade over the first two to four weeks as your body adjusts, and they are often stronger right after a dose increase. Older adults are more sensitive to the confusion, constipation, urinary retention, and blood pressure drops that lead to falls. Taking the dose at bedtime, standing up slowly, drinking water, and adding fiber handle most of the day-to-day problems. Tell your prescriber about any new twitching, muscle stiffness, or repetitive mouth movements, since those need prompt review rather than waiting.
Living with amoxapine: what to watch for
Common questions
What are the side effects of Amoxapine?
Amoxapine is a tricyclic-type antidepressant, so the frequent effects are drowsiness, dry mouth, constipation, blurred vision, dizziness on standing, weight gain, and trouble urinating. Most of these ease within the first few weeks. Because amoxapine also blocks dopamine, it can cause movement problems such as tremor, muscle stiffness, inner restlessness, or repetitive face and mouth movements that may persist, so report any new movement changes promptly. Like all antidepressants, it carries a warning about new or worsening suicidal thoughts, especially under age 25. Seek emergency care for high fever with muscle rigidity, a seizure, or a fast or irregular heartbeat.