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Short answer Living with amphotericin B: what to watch for Common questions Related questions Sources**Common side effects are fever, chills, nausea, infusion reactions, kidney injury, and low potassium or magnesium.**
Which effects you get depends on the formulation, dose, and your kidney health. Liposomal or lipid formulations cause fewer kidney problems than the older deoxycholate form. Your team will check blood tests and electrolytes regularly and may give premedication and a slower infusion to reduce reactions. Call your clinician if you have high fever, trouble breathing, fainting, little urine, or severe muscle weakness.
Living with amphotericin B: what to watch for
Common questions
What are the side effects of Amphotericin B Injection?
Amphotericin B injections often cause infusion-related reactions during or shortly after the dose, including fever, chills, rigors, headache, nausea, vomiting, low blood pressure, and chest or back pain. The medicine is also toxic to the kidneys and commonly produces low potassium and magnesium, and it can change liver tests and cause anemia. Lipid or liposomal products lower but do not eliminate kidney risk. Clinicians monitor kidney function and electrolytes, give premedication when needed, and adjust dose or switch formulations for serious toxicity. Seek urgent care for severe breathing trouble, very low urine output, fainting, irregular heartbeat, or marked weakness.