**ALS symptoms include progressive muscle weakness, twitching, cramps, and trouble speaking, swallowing, or breathing.**
You may first notice trouble gripping objects, buttoning clothes, or lifting your foot when walking. Symptoms usually develop gradually, and their starting point and pace vary. Twitching alone does not establish ALS, and other conditions can cause similar symptoms. Track changes in your daily activities and arrange a clinician visit for persistent or worsening weakness.
How ALS symptoms show up
Common questions
What are the symptoms of ALS - resources?
ALS, or amyotrophic lateral sclerosis, causes muscle weakness that worsens over time. You may notice repeated tripping, difficulty gripping objects, muscle twitching, cramps, stiffness, or slurred speech. Swallowing and breathing can also become difficult. These symptoms have other causes, so you need a clinician's assessment, sometimes with a neurologist and nerve or muscle tests. Arrange a visit for persistent or worsening weakness. Call 911 for severe breathing trouble or sudden weakness or speech changes. Use MedlinePlus and NHS resources to learn about symptoms, testing, and support.