What happens if you miss a dose of Adalimumab Injection?
Last updated September 7, 2026.
Inject the missed adalimumab dose as soon as you remember, then take your next dose at the originally scheduled time. The main exception is when you remember close to the next scheduled dose, since two injections a day or two apart increase your exposure without added benefit. In that case, ask your prescriber whether to skip the missed dose or shift the schedule. Keep the pen or syringe refrigerated until you use it, and let it sit at room temperature for about 15 to 30 minutes before injecting. A phone reminder on injection day plus the next date marked on a calendar prevents most missed doses. If you have been off adalimumab for several weeks, or you have a fever or another sign of infection, check with your clinician before you restart.
What to do
- Inject when you remember: Give the missed dose the same day you notice it, as long as your next dose is still several days out.
- Never double up: Do not inject two doses together or on the same day to make up for one you skipped.
- Keep the original schedule: After a late dose, return to your usual injection day rather than restarting the count from the late date.
- Call for close or long gaps: Ask your prescriber what to do if the next dose is a day or two away or if you have missed several weeks.
- Check the injection first: Look at the liquid for color changes or particles, and let the pen warm to room temperature before use.
- Hold if you feel sick: Contact your clinician before injecting if you have a fever, chills, cough, or an open skin infection.