What is the difference between salmonella and E. coli?

Last updated September 3, 2026.

Salmonella: onset in 12 to 72 hours, 4 to 7 days of diarrhea, fever, and cramps, usually self-limited, from poultry, eggs, and produce. E. coli is a family where most strains are harmless but Shiga toxin-producing ones like O157:H7 are particularly dangerous: sources are undercooked ground meat, raw milk, and contaminated vegetables and sprouts, and it can cause bloody diarrhea and a life-threatening kidney failure called hemolytic uremic syndrome, especially in children. Bloody diarrhea is the STEC tell; either way, cooking to temperature, washing produce and hands, and avoiding cross-contamination prevent both.

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