Why do I get a fever blister before big events?

Last updated September 3, 2026.

Fever blisters are the herpes simplex virus reactivating when your immune guard dips - and the run-up to big events manufactures that dip: late nights, feeling run down, sun exposure. The NHS lists illness, sunshine, and periods as triggers, and the tingle-itch-burn stage is your early warning. Antiviral cream works best at the tingle. Pymander is a free AI doctor, 24/7 by text, and can help.

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