Why do I get brain zaps when I miss my antidepressant?

Brain zaps - sudden brief electric-shock sensations in the head, sometimes shooting down the arms, often triggered by moving the eyes - are a documented withdrawal effect of antidepressants, especially SSRIs and SNRIs, appearing after missed doses, dose cuts, or stopping. They feel alarming and are not known to cause harm - they are the brain reacting to a sudden drop in serotonin signaling, and they fade as levels restabilize, typically within days of restarting or as a slow taper continues. NHS medication guidance is explicit that antidepressants should be reduced gradually rather than stopped suddenly for exactly this reason. What to do: if you missed one dose, take it when you remember - unless the next dose is near, in which case skip, never double - and set a daily alarm, since zaps after single missed doses mean your medication is one of the short-acting ones where timing matters. If you are stopping deliberately: do it with your prescriber over weeks to months, slower for long-term use, and pause the taper if zaps and dizziness get loud - taper speed is adjustable. When zaps mean more: withdrawal that comes with flu-like symptoms, intense dizziness, insomnia, irritability, or mood crash - the full discontinuation syndrome - deserves a call to your prescriber to slow the plan. And the mood side matters: if low mood or anxiety returns hard during a taper, that is information about whether this is the right time to come off, not failure. Pymander is a free AI doctor, 24/7 by text. Describe the zaps and your dosing, and it can help you plan the conversation with your prescriber.