Ezra vs Prenuvo: the two whole-body MRI companies compared

Last updated September 3, 2026.

Ezra and Prenuvo sell the same dream: catch cancer and serious disease years before symptoms, with a radiation-free whole-body MRI. They differ on price, speed, add-ons, and what happens with your results. Here is the honest comparison.

What do they cost?

Ezra's MRI scan starts at $899 with a Function membership, with a spine-inclusive version at $1,499 with membership, per its own site, and it notes scans may be HSA/FSA eligible. Prenuvo starts at $1,199 for its whole-body MRI, with memberships stacking on body composition and an advanced brain health scan, per its own site. Entry pricing favors Ezra, especially through the Function partnership; Prenuvo's tiers climb higher with more detailed imaging options.

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What is the scan experience?

Ezra emphasizes speed: its MRI looks at up to 13 organs in as little as 22 minutes, booked online with a medical questionnaire, and it offers add-ons like low-dose CT for coronary calcium and lung screening, plus couples pricing for back-to-back scans. Prenuvo emphasizes depth: its most detailed MRI captures 1.3 billion data points screening hundreds of conditions, with personalized results reviews and options to go deeper on brain and body composition. Ezra is the faster, more modular scan. Prenuvo is the more comprehensive imaging event.

Which one should you pick?

Price-sensitive or already a Function member: Ezra's $899 entry is hard to beat, and the CT add-ons cover what MRI misses in heart and lung. Maximum imaging detail and a clinic experience built around the scan: Prenuvo. Either way, go in clear-eyed about incidental findings, the harmless oddities these scans routinely surface that still cost follow-up care. And remember neither scan replaces symptom-driven medicine; Pymander's free AI doctor consult can help you think through whether screening fits your risk. Emergencies bypass all of it: call 911. Pymander routes emergency red flags to 911, and its escalation logic is documented in its safety architecture working paper.

What a Pymander AI doctor consult looks like

You said you turn 50 next month and want one big screening splurge. Any family history of cancer or aneurysm, and does the $300 to $400 difference between these two actually matter to you?
Family history: colon cancer, dad at 58. The price difference does not matter much. I want whichever one is most thorough for someone with my history.
Thanks for giving me all this information. Based on what you've said, there is a catch worth knowing before you splurge: neither MRI screens the colon, and with your father's history the colonoscopy is the scan that actually matters for you. Here's your care note to share with your care team.
Care note
Turning 50, colon history first
Turning 50, father had colon cancer at 58. Wants a whole-body MRI splurge. Key reframe: whole-body MRI does not screen the colon; with first-degree colon cancer history at that age, colonoscopy is the priority screening, and the MRI is optional add-on, not substitute.
View care note →

Illustrative example, not a real member's messages.

Common questions

How much does Ezra cost?

From $899 with a Function membership for its MRI scan covering up to 13 organs; $1,499 with membership for the spine-inclusive version, per its own site. HSA/FSA reimbursement may apply.

How much does Prenuvo cost?

From $1,199 for the whole-body MRI, with memberships adding body composition and an advanced brain health scan, per its own site.

What is the main difference between Ezra and Prenuvo?

Ezra is faster and more modular: 22-minute scans, CT add-ons for heart and lung, and lower entry pricing through its Function partnership. Prenuvo is the deeper imaging event: more data points per scan and a review experience built around it.

Do these scans replace colonoscopy or mammograms?

No. Whole-body MRI does not screen the colon effectively and does not replace mammography, Pap smears, or other guideline screenings. It complements them; it does not substitute.

What happens if a scan finds something?

Both provide results reviews. Any real finding gets referred into the medical system for follow-up imaging or biopsy, which is where incidental benign findings generate cost and worry. Go in expecting that possibility.

What if it is an emergency?

Screening is for the well; symptoms need care now. Call 911 for emergencies. Pymander is built to recognize emergency red flags and direct you to call rather than continue.

Sources

Pymander is not a replacement for a physician and does not provide medical advice, diagnosis, or treatment.

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