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In short Estradiol vaginal insert price by strength What Estradiol vaginal insert is Who looks up Estradiol vaginal insert Where to get Estradiol vaginal insert How Pymander fits Common questions SourcesEstradiol vaginal insert costs from $87.42 for a 30 count at Cost Plus Drugs, depending on strength. It is the generic of Vagifem.
Estradiol vaginal insert is a prescription medicine, so a licensed clinician has to decide it is right for you before a pharmacy can fill it. Prices as of October 11, 2026; no insurance needed.
Estradiol vaginal insert price by strength
| Strength | 30 count | 90 count | Cost Plus Drugs |
|---|---|---|---|
| 10 mcg | $87.42 | $252.25 | View |
A 30 count is 30 units of the product (pills, capsules or the pack size Cost Plus lists), not a promise of 30 days. These are Cost Plus Drugs’ own cash prices, including their pharmacy fee. Shipping is added at their checkout. Pymander adds no fee or markup. Prices checked October 11, 2026 and can change.
Of the 12 medications in the Women’s health group with a 30 count price in our catalog, Estradiol vaginal insert costs less than 4 of the others. The middle price for that group is $40.44.
What Estradiol vaginal insert is
This is a tiny estradiol tablet placed in the vagina. It rebuilds thin, dry vaginal tissue after menopause with a low dose.
What it’s for
Vaginal dryness, irritation and painful sex from menopause.
How it’s taken
Placed in the vagina with an applicator, once a day for 2 weeks, then twice a week.
Good to know
Low-dose vaginal estrogen puts much less into the blood than pills or patches. Even so, any vaginal bleeding after menopause should be checked, and people with a history of breast cancer or blood clots should discuss it first. Sudden chest pain, trouble breathing, sudden weakness or trouble speaking: call 911.
The plain-language description on this page was written from public medical sources and has not been reviewed by a clinician. Use it to get oriented, then check with your own clinician or pharmacist.
Who looks up Estradiol vaginal insert
People search for Estradiol vaginal insert when they are dealing with vaginal dryness, painful sex, menopause, vaginal atrophy, genitourinary syndrome of menopause. Estradiol vaginal insert is a prescription medicine, so a licensed clinician has to decide it is right for you before a pharmacy can fill it.
Where to get Estradiol vaginal insert
| Where | Price we can show | Note | Link |
|---|---|---|---|
| Cost Plus Drugs Mail-order pharmacy | $87.42 and up | Price includes their pharmacy fee. Shipping is per order. | Open |
| GoodRx Discount coupon | See price on their site | Free coupon prices at local pharmacies. Prices vary by pharmacy and ZIP code. | Open |
| Amazon Pharmacy Mail-order pharmacy | See price on their site | Search for this medication to see Amazon’s price. Prime members can add RxPass, a flat monthly fee for a list of common generics. | Open |
Only Cost Plus Drugs publishes a machine-readable price list, so it is the only price we quote. For the others we link to their pages and do not guess a number.
How Pymander fits
Pymander is an AI-native, cash-pay healthcare system. This catalog lists prices from outside sources so you can compare before you pay, and Pymander does not sell Estradiol vaginal insert or add a fee on top. You can text our free AI doctor with questions about a symptom or a medication, and bring the care note to the clinician who decides your treatment.
Common questions
How much does Estradiol vaginal insert cost without insurance?
Estradiol vaginal insert costs from $87.42 for a 30 count at Cost Plus Drugs, depending on strength (October 11, 2026). Insurance is not billed.
Do I need a prescription for Estradiol vaginal insert?
Estradiol vaginal insert is a prescription medicine, so a licensed clinician has to decide it is right for you before a pharmacy can fill it.
Is there a cheaper way to buy Estradiol vaginal insert?
Compare Cost Plus Drugs with a discount coupon such as GoodRx at a local pharmacy, since prices differ by pharmacy and ZIP code. Ask the pharmacy for its cash price in writing before you pay.
Does Pymander charge extra for Estradiol vaginal insert?
No. The prices on this page are the outside source’s own prices. Pymander adds no fee or markup.