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In short Levothyroxine price by strength What Levothyroxine is Who looks up Levothyroxine Where to get Levothyroxine How Pymander fits Common questions SourcesLevothyroxine costs from $5.91 for a 30 count at Cost Plus Drugs, depending on strength. It is the generic of Synthroid.
Levothyroxine is a prescription medicine, so a licensed clinician has to decide it is right for you before a pharmacy can fill it. Prices as of October 11, 2026; no insurance needed.
Levothyroxine price by strength
| Strength | 30 count | 90 count | Cost Plus Drugs |
|---|---|---|---|
| 25 mcg | $5.91 | $7.73 | View |
| 50 mcg | $5.91 | $7.74 | View |
| 75 mcg | $5.95 | $7.84 | View |
| 88 mcg | $5.94 | $7.83 | View |
| 100 mcg | $6.09 | $8.28 | View |
| 125 mcg | $6.08 | $8.23 | View |
A 30 count is 30 units of the product (pills, capsules or the pack size Cost Plus lists), not a promise of 30 days. These are Cost Plus Drugs’ own cash prices, including their pharmacy fee. Shipping is added at their checkout. Pymander adds no fee or markup. Prices checked October 11, 2026 and can change.
Of the 11 medications in the Thyroid & hormones group with a 30 count price in our catalog, Levothyroxine has the lowest price. The middle price for that group is $12.45.
What Levothyroxine is
Levothyroxine is a man-made form of T4, the main thyroid hormone. It replaces the hormone when the thyroid doesn’t make enough.
What it’s for
Underactive thyroid (hypothyroidism), and after thyroid surgery or treatment.
How it’s taken
By mouth, once a day on an empty stomach with water, 30 to 60 minutes before breakfast. Calcium, iron and antacids are taken at least 4 hours apart. Blood tests (TSH) guide the dose.
Good to know
It has a boxed warning: thyroid hormone must not be used to lose weight. In people with normal thyroid levels it won’t help, and large doses can cause serious or life-threatening effects. Too high a dose can cause a racing heart, shakiness, trouble sleeping and bone loss; chest pain or a very fast or uneven heartbeat needs care right away.
The plain-language description on this page was written from public medical sources and has not been reviewed by a clinician. Use it to get oriented, then check with your own clinician or pharmacist.
Who looks up Levothyroxine
People search for Levothyroxine when they are dealing with hypothyroidism, underactive thyroid, Hashimoto’s, thyroid replacement, goiter. Levothyroxine is a prescription medicine, so a licensed clinician has to decide it is right for you before a pharmacy can fill it.
For more on what it treats and how it is taken, see Levothyroxine: what it treats, how to take it.
Where to get Levothyroxine
| Where | Price we can show | Note | Link |
|---|---|---|---|
| Cost Plus Drugs Mail-order pharmacy | $5.91 and up | Price includes their pharmacy fee. Shipping is per order. | Open |
| GoodRx Discount coupon | See price on their site | Free coupon prices at local pharmacies. Prices vary by pharmacy and ZIP code. | Open |
| Amazon Pharmacy Mail-order pharmacy | See price on their site | Search for this medication to see Amazon’s price. Prime members can add RxPass, a flat monthly fee for a list of common generics. | Open |
Only Cost Plus Drugs publishes a machine-readable price list, so it is the only price we quote. For the others we link to their pages and do not guess a number.
How Pymander fits
Pymander is an AI-native, cash-pay healthcare system. This catalog lists prices from outside sources so you can compare before you pay, and Pymander does not sell Levothyroxine or add a fee on top. You can text our free AI doctor with questions about a symptom or a medication, and bring the care note to the clinician who decides your treatment.
Common questions
How much does Levothyroxine cost without insurance?
Levothyroxine costs from $5.91 for a 30 count at Cost Plus Drugs, depending on strength (October 11, 2026). Insurance is not billed.
Do I need a prescription for Levothyroxine?
Levothyroxine is a prescription medicine, so a licensed clinician has to decide it is right for you before a pharmacy can fill it.
Is there a cheaper way to buy Levothyroxine?
Compare Cost Plus Drugs with a discount coupon such as GoodRx at a local pharmacy, since prices differ by pharmacy and ZIP code. Ask the pharmacy for its cash price in writing before you pay.
Does Pymander charge extra for Levothyroxine?
No. The prices on this page are the outside source’s own prices. Pymander adds no fee or markup.