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In short Mesalamine price by strength What Mesalamine is Who looks up Mesalamine Where to get Mesalamine How Pymander fits Common questions SourcesMesalamine costs from $21.10 for a 30 count at Cost Plus Drugs, depending on strength. It is the generic of Lialda.
Mesalamine is a prescription medicine, so a licensed clinician has to decide it is right for you before a pharmacy can fill it. Prices as of October 11, 2026; no insurance needed.
Mesalamine price by strength
| Strength | 30 count | 90 count | Cost Plus Drugs |
|---|---|---|---|
| 400 mg | $61.36 | $174.07 | View |
| 800 mg | $97.41 | $282.22 | View |
| 1,200 mg | $21.10 | $53.30 | View |
A 30 count is 30 units of the product (pills, capsules or the pack size Cost Plus lists), not a promise of 30 days. These are Cost Plus Drugs’ own cash prices, including their pharmacy fee. Shipping is added at their checkout. Pymander adds no fee or markup. Prices checked October 11, 2026 and can change.
Of the 44 medications in the Stomach & digestion group with a 30 count price in our catalog, Mesalamine costs less than 14 of the others. The middle price for that group is $10.45.
What Mesalamine is
Mesalamine calms inflammation right at the lining of the colon. It is a mainstay for mild to moderate ulcerative colitis.
What it’s for
Bringing ulcerative colitis under control and keeping it in remission.
How it’s taken
By mouth once to several times a day, depending on the brand. Suppository and enema forms treat the lower colon.
Good to know
It can rarely harm the kidneys, so kidney blood tests are done over time. A rare reaction can look like a colitis flare (cramps, bloody diarrhea, fever). People allergic to aspirin or salicylates should say so.
When to get help
Vomiting blood or what looks like coffee grounds, black or tarry stools, or severe belly pain need care right away: call 911 or go to the ER.
The plain-language description on this page was written from public medical sources and has not been reviewed by a clinician. Use it to get oriented, then check with your own clinician or pharmacist.
Who looks up Mesalamine
People search for Mesalamine when they are dealing with ulcerative colitis, inflammatory bowel disease, IBD. Mesalamine is a prescription medicine, so a licensed clinician has to decide it is right for you before a pharmacy can fill it.
For more on what it treats and how it is taken, see Mesalamine: what it treats, how to take it.
Where to get Mesalamine
| Where | Price we can show | Note | Link |
|---|---|---|---|
| Cost Plus Drugs Mail-order pharmacy | $21.10 and up | Price includes their pharmacy fee. Shipping is per order. | Open |
| GoodRx Discount coupon | See price on their site | Free coupon prices at local pharmacies. Prices vary by pharmacy and ZIP code. | Open |
| Amazon Pharmacy Mail-order pharmacy | See price on their site | Search for this medication to see Amazon’s price. Prime members can add RxPass, a flat monthly fee for a list of common generics. | Open |
Only Cost Plus Drugs publishes a machine-readable price list, so it is the only price we quote. For the others we link to their pages and do not guess a number.
How Pymander fits
Pymander is an AI-native, cash-pay healthcare system. This catalog lists prices from outside sources so you can compare before you pay, and Pymander does not sell Mesalamine or add a fee on top. You can text our free AI doctor with questions about a symptom or a medication, and bring the care note to the clinician who decides your treatment.
Common questions
How much does Mesalamine cost without insurance?
Mesalamine costs from $21.10 for a 30 count at Cost Plus Drugs, depending on strength (October 11, 2026). Insurance is not billed.
Do I need a prescription for Mesalamine?
Mesalamine is a prescription medicine, so a licensed clinician has to decide it is right for you before a pharmacy can fill it.
Is there a cheaper way to buy Mesalamine?
Compare Cost Plus Drugs with a discount coupon such as GoodRx at a local pharmacy, since prices differ by pharmacy and ZIP code. Ask the pharmacy for its cash price in writing before you pay.
Does Pymander charge extra for Mesalamine?
No. The prices on this page are the outside source’s own prices. Pymander adds no fee or markup.