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Ondansetron cost without insurance

Prices as of October 11, 2026PrescriptionStomach & digestion
On this pageIn short Ondansetron price by strength What Ondansetron is Who looks up Ondansetron Where to get Ondansetron How Pymander fits Common questions Sources
In short

Ondansetron costs from $6.17 for a 30 count at Cost Plus Drugs, depending on strength. It is the generic of Zofran.

Ondansetron is a prescription medicine, so a licensed clinician has to decide it is right for you before a pharmacy can fill it. Prices as of October 11, 2026; no insurance needed.

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Ondansetron price by strength

Strength30 count90 countCost Plus Drugs
4 mg$6.17$8.52View
8 mg$8.09$14.26View

A 30 count is 30 units of the product (pills, capsules or the pack size Cost Plus lists), not a promise of 30 days. These are Cost Plus Drugs’ own cash prices, including their pharmacy fee. Shipping is added at their checkout. Pymander adds no fee or markup. Prices checked October 11, 2026 and can change.

Of the 44 medications in the Stomach & digestion group with a 30 count price in our catalog, Ondansetron costs less than 36 of the others. The middle price for that group is $10.45.

What Ondansetron is

Ondansetron blocks serotonin signals in the gut and brain that trigger nausea and vomiting.

What it’s for

Preventing and treating nausea and vomiting, for example after surgery or chemotherapy, and often for a stomach bug.

How it’s taken

As needed, usually every 8 hours. A melt-on-the-tongue (ODT) version helps when keeping pills down is hard.

Good to know

It can affect heart rhythm (QT prolongation), especially with other medicines that do the same. Constipation and headache are common. Fainting or a racing, uneven heartbeat: call 911.

When to get help

Can’t keep fluids down, signs of dehydration, vomiting blood, black stools, or severe belly pain need care right away; call 911 or go to the ER for blood or severe pain.

The plain-language description on this page was written from public medical sources and has not been reviewed by a clinician. Use it to get oriented, then check with your own clinician or pharmacist.

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Who looks up Ondansetron

People search for Ondansetron when they are dealing with nausea, vomiting, stomach bug, motion sickness, chemotherapy nausea. Ondansetron is a prescription medicine, so a licensed clinician has to decide it is right for you before a pharmacy can fill it.

For more on what it treats and how it is taken, see Ondansetron: what it treats, how to take it.

Where to get Ondansetron

WherePrice we can showNoteLink
Cost Plus Drugs
Mail-order pharmacy
$6.17 and upPrice includes their pharmacy fee. Shipping is per order.Open
GoodRx
Discount coupon
See price on their siteFree coupon prices at local pharmacies. Prices vary by pharmacy and ZIP code.Open
Amazon Pharmacy
Mail-order pharmacy
See price on their siteSearch for this medication to see Amazon’s price. Prime members can add RxPass, a flat monthly fee for a list of common generics.Open

Only Cost Plus Drugs publishes a machine-readable price list, so it is the only price we quote. For the others we link to their pages and do not guess a number.

How Pymander fits

Pymander is an AI-native, cash-pay healthcare system. This catalog lists prices from outside sources so you can compare before you pay, and Pymander does not sell Ondansetron or add a fee on top. You can text our free AI doctor with questions about a symptom or a medication, and bring the care note to the clinician who decides your treatment.

Common questions

How much does Ondansetron cost without insurance?

Ondansetron costs from $6.17 for a 30 count at Cost Plus Drugs, depending on strength (October 11, 2026). Insurance is not billed.

Do I need a prescription for Ondansetron?

Ondansetron is a prescription medicine, so a licensed clinician has to decide it is right for you before a pharmacy can fill it.

Is there a cheaper way to buy Ondansetron?

Compare Cost Plus Drugs with a discount coupon such as GoodRx at a local pharmacy, since prices differ by pharmacy and ZIP code. Ask the pharmacy for its cash price in writing before you pay.

Does Pymander charge extra for Ondansetron?

No. The prices on this page are the outside source’s own prices. Pymander adds no fee or markup.

Other stomach & digestion medication prices

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