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Tizanidine cost without insurance

Prices as of October 11, 2026PrescriptionPain & inflammation
On this pageIn short Tizanidine price by strength What Tizanidine is Who looks up Tizanidine Where to get Tizanidine How Pymander fits Common questions Sources
In short

Tizanidine costs from $5.37 for a 30 count at Cost Plus Drugs, depending on strength. It is the generic of Zanaflex.

Tizanidine is a prescription medicine, so a licensed clinician has to decide it is right for you before a pharmacy can fill it. Prices as of October 11, 2026; no insurance needed.

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Tizanidine price by strength

Strength30 count90 countCost Plus Drugs
2 mg$5.37$6.11View
4 mg$5.62$6.86View
6 mg$7.99$13.96View

A 30 count is 30 units of the product (pills, capsules or the pack size Cost Plus lists), not a promise of 30 days. These are Cost Plus Drugs’ own cash prices, including their pharmacy fee. Shipping is added at their checkout. Pymander adds no fee or markup. Prices checked October 11, 2026 and can change.

Of the 31 medications in the Pain & inflammation group with a 30 count price in our catalog, Tizanidine costs less than 27 of the others. The middle price for that group is $9.67.

What Tizanidine is

A muscle relaxer that calms nerve signals that make muscles tight.

What it’s for

Muscle stiffness (spasticity) from MS, spinal cord injury or stroke. It’s also used off-label for muscle spasm.

How it’s taken

By mouth, usually every 6 to 8 hours as needed, taken the same way each time (always with food or always without).

Good to know

It can drop blood pressure and cause fainting and sleepiness. It must not be taken with ciprofloxacin or fluvoxamine, which raise its level sharply. It can affect the liver. Don’t stop high doses suddenly.

The plain-language description on this page was written from public medical sources and has not been reviewed by a clinician. Use it to get oriented, then check with your own clinician or pharmacist.

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Who looks up Tizanidine

People search for Tizanidine when they are dealing with spasticity, muscle spasm, multiple sclerosis, spinal cord injury, back pain. Tizanidine is a prescription medicine, so a licensed clinician has to decide it is right for you before a pharmacy can fill it.

For more on what it treats and how it is taken, see Tizanidine: what it treats, how to take it.

Where to get Tizanidine

WherePrice we can showNoteLink
Cost Plus Drugs
Mail-order pharmacy
$5.37 and upPrice includes their pharmacy fee. Shipping is per order.Open
GoodRx
Discount coupon
See price on their siteFree coupon prices at local pharmacies. Prices vary by pharmacy and ZIP code.Open
Amazon Pharmacy
Mail-order pharmacy
See price on their siteSearch for this medication to see Amazon’s price. Prime members can add RxPass, a flat monthly fee for a list of common generics.Open

Only Cost Plus Drugs publishes a machine-readable price list, so it is the only price we quote. For the others we link to their pages and do not guess a number.

How Pymander fits

Pymander is an AI-native, cash-pay healthcare system. This catalog lists prices from outside sources so you can compare before you pay, and Pymander does not sell Tizanidine or add a fee on top. You can text our free AI doctor with questions about a symptom or a medication, and bring the care note to the clinician who decides your treatment.

Common questions

How much does Tizanidine cost without insurance?

Tizanidine costs from $5.37 for a 30 count at Cost Plus Drugs, depending on strength (October 11, 2026). Insurance is not billed.

Do I need a prescription for Tizanidine?

Tizanidine is a prescription medicine, so a licensed clinician has to decide it is right for you before a pharmacy can fill it.

Is there a cheaper way to buy Tizanidine?

Compare Cost Plus Drugs with a discount coupon such as GoodRx at a local pharmacy, since prices differ by pharmacy and ZIP code. Ask the pharmacy for its cash price in writing before you pay.

Does Pymander charge extra for Tizanidine?

No. The prices on this page are the outside source’s own prices. Pymander adds no fee or markup.

Other pain & inflammation medication prices

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