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In short Tretinoin cream price by strength What Tretinoin cream is Who looks up Tretinoin cream Where to get Tretinoin cream How Pymander fits Common questions SourcesTretinoin cream costs from $14.17 for one fill (20 g tube) at Cost Plus Drugs, depending on strength. It is the generic of Retin-A.
Tretinoin cream is a prescription medicine, so a licensed clinician has to decide it is right for you before a pharmacy can fill it. Prices as of October 11, 2026; no insurance needed.
Tretinoin cream price by strength
| Strength | Price per fill | Pack | Cost Plus Drugs |
|---|---|---|---|
| 0.025% | $14.17 | Tube of Cream, 20 g | View |
| 0.05% | $26.17 | Tube of Cream, 20 g | View |
| 0.1% | $25.24 | Tube of Cream, 20 g | View |
A 30 count is 30 units of the product (pills, capsules or the pack size Cost Plus lists), not a promise of 30 days. These are Cost Plus Drugs’ own cash prices, including their pharmacy fee. Shipping is added at their checkout. Pymander adds no fee or markup. Prices checked October 11, 2026 and can change.
Of the 71 medications in the Skin group priced per fill in our catalog, Tretinoin cream costs less than 43 of the others. The middle price for that group is $17.32.
What Tretinoin cream is
A vitamin A cream (a retinoid) that speeds up how fast skin cells turn over. This helps unclog pores and, over months, smooths fine lines and evens out tone.
What it’s for
Acne, especially clogged pores. It’s also used for fine lines and sun-damaged skin.
How it’s taken
A pea-sized amount spread thin on dry skin at night. Many people start every other night while the skin gets used to it.
Good to know
Dryness, peeling and redness are common in the first weeks. It makes skin burn more easily, so use sunscreen. Not for use in pregnancy.
The plain-language description on this page was written from public medical sources and has not been reviewed by a clinician. Use it to get oriented, then check with your own clinician or pharmacist.
Who looks up Tretinoin cream
People search for Tretinoin cream when they are dealing with acne, blackheads, whiteheads, wrinkles, fine lines, sun damage, dark spots, anti-aging. Tretinoin cream is a prescription medicine, so a licensed clinician has to decide it is right for you before a pharmacy can fill it.
Where to get Tretinoin cream
| Where | Price we can show | Note | Link |
|---|---|---|---|
| Cost Plus Drugs Mail-order pharmacy | $14.17 and up | Price includes their pharmacy fee. Shipping is per order. | Open |
| GoodRx Discount coupon | See price on their site | Free coupon prices at local pharmacies. Prices vary by pharmacy and ZIP code. | Open |
| Amazon Pharmacy Mail-order pharmacy | See price on their site | Search for this medication to see Amazon’s price. Prime members can add RxPass, a flat monthly fee for a list of common generics. | Open |
Only Cost Plus Drugs publishes a machine-readable price list, so it is the only price we quote. For the others we link to their pages and do not guess a number.
How Pymander fits
Pymander is an AI-native, cash-pay healthcare system. This catalog lists prices from outside sources so you can compare before you pay, and Pymander does not sell Tretinoin cream or add a fee on top. You can text our free AI doctor with questions about a symptom or a medication, and bring the care note to the clinician who decides your treatment.
Common questions
How much does Tretinoin cream cost without insurance?
Tretinoin cream costs from $14.17 for one fill (20 g tube) at Cost Plus Drugs, depending on strength (October 11, 2026). Insurance is not billed.
Do I need a prescription for Tretinoin cream?
Tretinoin cream is a prescription medicine, so a licensed clinician has to decide it is right for you before a pharmacy can fill it.
Is there a cheaper way to buy Tretinoin cream?
Compare Cost Plus Drugs with a discount coupon such as GoodRx at a local pharmacy, since prices differ by pharmacy and ZIP code. Ask the pharmacy for its cash price in writing before you pay.
Does Pymander charge extra for Tretinoin cream?
No. The prices on this page are the outside source’s own prices. Pymander adds no fee or markup.