First tell your prescriber or pharmacist, then file a report with FDA MedWatch.
MedWatch is the FDA's safety reporting program, and it accepts reports directly from patients - online or by phone. You do not need to prove the drug caused the problem; the program exists to collect patterns, and your report is how rare dangers surface after approval.
What to do
Common questions
How do I report a medication side effect?
Tell your prescriber or pharmacist first - they can tell you whether what you are feeling is a known side effect, a dose problem, or something that needs a medication change. Then report it to the FDA through MedWatch, the agency's safety reporting program, which accepts reports from patients directly, online or by phone. This is worth doing even when you are not sure the drug caused the problem; MedWatch exists precisely to collect patterns, and a serious reaction - one that lands you in the hospital, causes lasting harm, or is simply unexpected and severe - is exactly what the FDA wants logged. Individual reports are how rare dangers surface years after approval. Keep the basics handy when you report: the drug name and strength, when you started it, what happened, and any other medications you take. Pymander, a free AI doctor available 24/7 by text, can help you organize those details before you file.