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How can you prevent ABO incompatibility?

Updated Oct 20, 20261 min readAnswer
On this pageShort answer Can it be prevented? Common questions Related questions Sources
Short answer

**Blood compatibility testing helps prevent ABO transfusion reactions, but you cannot prevent an inherited blood type difference between you and your baby.**

Before a transfusion, your care team checks your blood type and tests donor blood for compatibility. You can help by confirming your name and date of birth and reporting previous transfusion reactions. During pregnancy, routine blood testing identifies your blood group, but it cannot change your baby's inherited blood type. If your baby has a different ABO type, newborn monitoring helps detect jaundice or anemia that needs treatment.

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Can it be prevented?

1**Confirm your identity:**Check that staff have your correct name and date of birth before a blood transfusion.
2**Share your history:**Tell your care team about any previous transfusions or transfusion reactions.
3**Report symptoms promptly:**Tell staff immediately if you develop chills, fever, back pain, or trouble breathing during a transfusion.
4**Keep prenatal visits:**Complete recommended blood tests and discuss blood group concerns with your pregnancy care clinician.
5**Attend newborn checks:**Follow your baby's discharge plan for jaundice assessment and any recommended bilirubin testing.
6**Act on early jaundice:**Get immediate medical assessment if your baby's skin or eyes turn yellow in the first 24 hours.

Common questions

How can you prevent ABO incompatibility?

Preventing ABO transfusion reactions depends on blood typing, compatibility testing, and correct patient identification before blood is given. Confirm your name and date of birth with staff and share any past transfusion reactions. In pregnancy, you cannot prevent an inherited ABO blood type mismatch with your baby. Keep prenatal visits and your baby's recommended jaundice checks to catch problems early. Rh immune globulin prevents certain Rh problems, not ABO incompatibility. Get immediate medical assessment if your baby develops jaundice in the first 24 hours.

About this page. Written and maintained by the Pymander Health team. Last updated September 6, 2026.

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