How can you prevent Alkaptonuria?
Last updated September 7, 2026.
**You cannot prevent alkaptonuria through diet, exercise, or other lifestyle changes because it is inherited.** You develop this condition when you inherit an altered copy of the HGD gene from each parent. If alkaptonuria runs in your family, genetic counseling before pregnancy can help you understand your chances of passing it on. Carrier testing can guide discussions about your reproductive options. If you already have alkaptonuria, work with your clinician to manage symptoms and ask for dietitian guidance before restricting protein.
What to do
- **Review your family history:** Tell your clinician if a relative has alkaptonuria.
- **Plan before pregnancy:** Ask a genetic counselor about carrier testing and your reproductive options.
- **Get urine changes checked:** Contact your clinician if your urine turns dark brown or black after exposure to air.
- **Discuss joint symptoms:** Ask your clinician whether physical therapy could help your pain and movement.
- **Get nutrition guidance:** Consult a dietitian before starting a protein restriction.
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