Is Agitation serious?
Last updated September 7, 2026.
**Agitation can be serious, especially when you also have sudden confusion or trouble staying alert.** You may feel restless, tense, or irritable during stress without having a serious illness. Medicines, infections, pain, and alcohol or drug withdrawal can also cause agitation. A clinician should assess symptoms that are severe, persistent, or unexplained. For mild symptoms, a quiet setting, regular sleep, and less caffeine may help.
What to do
- **Recognize urgent changes:** Get immediate medical care if your agitation comes with sudden confusion or reduced alertness.
- **Get crisis support:** Call or text 988 for thoughts of suicide, or call 911 if you are in immediate danger.
- **Arrange an assessment:** Contact a clinician if your agitation is severe, persistent, or unexplained.
- **Review possible triggers:** Tell your clinician about new medicines, dose changes, and changes in alcohol or drug use.
- **Create a calmer setting:** Reduce noise and stimulation when you feel agitated.
- **Support your sleep:** Keep a regular sleep schedule and reduce caffeine if it increases your restlessness.
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