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Short answer Amisulpride and dependence: what to know Common questions Related questions SourcesNo, amisulpride injection is not addictive and is not a controlled substance in the United States.
In the US it is approved as Barhemsys, given through an IV to prevent or treat nausea and vomiting around surgery, usually as a single dose while you are still in the hospital or surgery center. It blocks dopamine receptors in the part of the brain that triggers vomiting, and it does not produce a high, cravings, or a withdrawal syndrome when it stops. Because treatment is so short, tolerance and dose escalation are not concerns either. The issues worth watching are different ones: it can lengthen the QT interval on an ECG, so your team needs to know about heart rhythm problems, low potassium or magnesium, kidney disease, and every other medicine you take. Confusing it with long term oral amisulpride used in some countries for psychosis is common, and even that oral form is not addictive, though it should never be stopped abruptly without medical advice.
Amisulpride and dependence: what to know
Common questions
Is Amisulpride Injection addictive?
No. Amisulpride injection (Barhemsys in the US) is not a controlled substance and does not cause addiction. It is a dopamine antagonist given through an IV to prevent or treat nausea and vomiting after surgery, usually as one dose during your hospital or surgery center visit. It does not produce a high, and people do not develop cravings or withdrawal after it. Since treatment lasts a day at most, tolerance is not an issue. Reported effects include chills, low potassium, and infusion site pain. Tell your care team about heart rhythm problems, kidney disease, or Parkinson disease, since amisulpride can affect the QT interval and dopamine blockers can worsen Parkinson symptoms.