Is Ceftolozane and Tazobactam Injection addictive?
Last updated September 7, 2026.
**No, ceftolozane and tazobactam injection is not addictive.** This antibiotic combination, sold as Zerbaxa, treats certain bacterial infections through an infusion into your vein. It does not cause cravings or withdrawal, and you do not need to taper it to prevent withdrawal. Your treatment length depends on your infection and response, so follow your prescribing clinician's instructions. Antibiotic resistance means bacteria become harder to treat; it does not mean your body is addicted.
What to do
- **Follow your schedule:** Receive each dose as prescribed and ask your care team what to do if you miss an infusion.
- **Discuss treatment changes:** Ask your prescribing clinician before stopping early, even if you feel better.
- **Report ongoing symptoms:** Contact your clinician if your infection symptoms worsen or remain after treatment.
- **Report severe diarrhea:** Contact your clinician promptly for watery or bloody diarrhea during or after treatment.
- **Get emergency help:** Call 911 if you develop trouble breathing or swelling of your face, tongue, or throat.
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