What causes Anorectal abscess?

Last updated September 7, 2026.

**Most anorectal abscesses start when one of the tiny glands inside the anal canal gets blocked and infected, so bacteria multiply and pus collects in the tissue around it.** The picture changes when something else is driving it: Crohn's disease, an anal fissure, a sexually transmitted infection, or injury from trauma, childbirth, or previous surgery can all set one off. Weakened immune defenses from diabetes, HIV, cancer treatment, or long-term steroid use make an abscess more likely and slower to clear. Abscesses that keep coming back, or that sit in unusual places, point toward an underlying condition worth testing for, especially Crohn's disease. Keeping stool soft with fiber, fluids, and prompt treatment of constipation limits irritation of the anal canal, and warm sitz baths ease early soreness. An abscess almost always needs drainage by a clinician, so a firm, swollen, painful lump near the anus is a reason to be seen quickly.

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