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What is Alvimopan used for?

Updated Sep 7, 20261 min readAnswer
On this pageShort answer Starting alvimopan: what to know Common questions Related questions Sources
Short answer

**Alvimopan helps your bowel recover faster after surgery that removes part of your bowel and reconnects the remaining ends.**

It blocks the bowel-slowing effects of opioid pain medicines, helping you return to eating solid food and passing stool. You receive it only in the hospital, starting before surgery, with no more than 15 doses total. Your surgeon must review your recent opioid use because taking opioids for more than seven consecutive days immediately beforehand rules out alvimopan. Follow your surgical team's instructions for eating, drinking, and moving during recovery.

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Starting alvimopan: what to know

1**Review your medicines:**Tell your surgeon which opioid medicines you have taken recently and for how long.
2**Share your medical history:**Tell your care team about bowel blockages, kidney or liver disease, pregnancy, or breastfeeding.
3**Understand the limit:**You receive no more than 15 doses in the hospital because prolonged use carries a potential heart attack risk.
4**Follow your recovery plan:**Follow your surgical team's instructions about when to eat, drink, and walk.
5**Report symptoms:**Tell your hospital team promptly if you develop worsening belly pain, vomiting, or diarrhea.

Common questions

What is Alvimopan used for?

Alvimopan is a hospital medicine that helps your digestive system recover after surgery to remove part of your bowel and reconnect the ends. It blocks opioid effects in your gut, helping you eat solid food and pass stool sooner. You receive a dose before surgery, then twice daily starting the next day, for up to seven days after surgery or until discharge, whichever comes first. Treatment is limited to 15 doses. It is not a home treatment for constipation. Tell your surgeon about all recent opioid use: alvimopan must not be used if you took opioids for more than seven consecutive days immediately beforehand.

About this page. Written and maintained by the Pymander Health team. Last updated September 7, 2026.

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