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Short answer Starting anifrolumab: what to know Common questions Related questions Sources**Anifrolumab-fnia injection (Saphnelo) treats moderate to severe systemic lupus erythematosus in adults receiving standard lupus treatment.**
It blocks signals from type I interferons, proteins involved in immune activity, to help control your lupus. You receive it as an infusion into a vein every 4 weeks or an injection under your skin once weekly. It is not recommended if you have severe active lupus affecting your kidneys or central nervous system. Your rheumatologist should assess whether it fits your treatment plan, and you should review your medicines and vaccinations before starting.
Starting anifrolumab: what to know
Common questions
What is Anifrolumab-fnia Injection used for?
Anifrolumab-fnia (Saphnelo) treats moderate to severe systemic lupus erythematosus in adults already taking standard lupus medicines. It helps control your disease by blocking immune signals called type I interferons, but it does not cure lupus. You receive a 30-minute IV infusion every 4 weeks or an injection under your skin once weekly. It is not recommended for severe active lupus nephritis or central nervous system lupus. Your rheumatologist decides whether it suits you. Report infection symptoms promptly and avoid live vaccines during treatment.