What medications cause nausea?

Last updated September 3, 2026.

MedlinePlus names GLP-1 diabetes and obesity drugs, chemotherapy, radiation, and opioids among the nausea causers; iron, antibiotics, metformin, and early-course antidepressants fill out the everyday list. Mechanisms range from slowed stomach emptying to direct brainstem triggering. Tactics: food when the label allows, low-and-slow titration for GLP-1s, split iron doses with a snack if needed, and standard anti-nausea cover for chemo and opioids. Tell the prescriber before quitting, since gentler family members usually exist, and get seen if vomiting blocks all fluids and medicines.

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