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What screenings do I need at 40?

Updated Sep 3, 20261 min readAnswer
On this pageShort answer What to do Common questions Related questions Sources
Short answer

At 40 the list grows. Women: mammograms begin - the USPSTF recommends every 2 years from 40 to 74 at average risk; strong family history moves the conversation earlier. Everyone: colorectal screening starts at 45 - pick the type now (home stool tests vs colonoscopy). And the continuing core: blood pressure, cholesterol, blood sugar screening (type 2 diabetes clusters in this decade), women's cervical screening on its schedule.

Plus the quiet ones: an eye exam (vision shifts in the forties; glaucoma screening with family history), dental, skin checks, and vaccine maintenance - flu yearly, Tdap/Td booster, COVID current, per the CDC. Pymander is a free AI doctor, 24/7 by text, and can build your personal list.

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What to do

1Women: book the first mammogram:every 2 years, 40 to 74.
2Everyone: plan colorectal screening for 45:choose the test type now.
3Keep BP, cholesterol, and sugar on a cycle:this decade sets the trajectory.
4Add the eye exam:the forgotten forty-something screening.

Common questions

What screenings do I need at 40?

Forty is the decade screening gets real - the tests that were 'not yet' start arriving. For women: mammograms begin - the US Preventive Services Task Force recommends women at average risk get one every 2 years from 40 to 74, per the CDC's screening guidance; earlier and more often with a strong family history, which is a conversation to have at 40, not 50. For everyone: colorectal screening is close - the CDC says begin soon after turning 45 - so 40 is when to put it on the calendar and ask which type (stool tests at home versus colonoscopy). The continuing list from your thirties keeps running: blood pressure at visits, cholesterol on a regular cycle (and statin conversations begin for many in this decade if risk adds up), blood sugar screening - type 2 diabetes onset clusters here, especially with extra weight or family history; cervical screening continues for women per the schedule you and your doctor chose. Do not forget the quiet ones: an eye exam (reading vision shifts in the forties, and glaucoma screening matters with family history), dental cleanings, skin checks, and the vaccine maintenance - flu yearly, Tdap/Td booster, COVID current, per the CDC. Pymander is a free AI doctor, 24/7 by text, that can build your personal list from your history and risk factors.

About this page. Written and maintained by the Pymander Health team. Last updated September 3, 2026.

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