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In short Adapalene gel price by strength What Adapalene gel is Who looks up Adapalene gel Where to get Adapalene gel How Pymander fits Common questions SourcesAdapalene gel costs from $16.57 for one fill (45 g tube) at Cost Plus Drugs, depending on strength. It is the generic of Differin.
Adapalene gel is sold over the counter, so you do not need a prescription. Prices as of October 11, 2026; no insurance needed.
Adapalene gel price by strength
| Strength | Price per fill | Pack | Cost Plus Drugs |
|---|---|---|---|
| 0.3% | $16.57 | Tube of Gel, 45 g | View |
A 30 count is 30 units of the product (pills, capsules or the pack size Cost Plus lists), not a promise of 30 days. These are Cost Plus Drugs’ own cash prices, including their pharmacy fee. Shipping is added at their checkout. Pymander adds no fee or markup. Prices checked October 11, 2026 and can change.
Of the 71 medications in the Skin group priced per fill in our catalog, Adapalene gel costs less than 38 of the others. The middle price for that group is $17.32.
What Adapalene gel is
A retinoid gel that calms acne and keeps pores clear. It tends to be gentler than tretinoin.
What it’s for
Acne. The 0.1% gel is sold over the counter; the stronger 0.3% gel needs a prescription.
How it’s taken
A thin layer over the whole area with acne, once a day at night, on clean, dry skin.
Good to know
Dryness and mild stinging are common at first. It can take about three months to see the full effect. Use sunscreen. Ask a clinician before using it in pregnancy.
The plain-language description on this page was written from public medical sources and has not been reviewed by a clinician. Use it to get oriented, then check with your own clinician or pharmacist.
Who looks up Adapalene gel
People search for Adapalene gel when they are dealing with acne, blackheads, whiteheads, clogged pores, pimples. Adapalene gel is sold over the counter, so you do not need a prescription.
Where to get Adapalene gel
| Where | Price we can show | Note | Link |
|---|---|---|---|
| Cost Plus Drugs Mail-order pharmacy | $16.57 and up | Price includes their pharmacy fee. Shipping is per order. | Open |
| GoodRx Discount coupon | See price on their site | Free coupon prices at local pharmacies. Prices vary by pharmacy and ZIP code. | Open |
Only Cost Plus Drugs publishes a machine-readable price list, so it is the only price we quote. For the others we link to their pages and do not guess a number.
How Pymander fits
Pymander is an AI-native, cash-pay healthcare system. This catalog lists prices from outside sources so you can compare before you pay, and Pymander does not sell Adapalene gel or add a fee on top. You can text our free AI doctor with questions about a symptom or a medication, and bring the care note to the clinician who decides your treatment.
Common questions
How much does Adapalene gel cost without insurance?
Adapalene gel costs from $16.57 for one fill (45 g tube) at Cost Plus Drugs, depending on strength (October 11, 2026). Insurance is not billed.
Do I need a prescription for Adapalene gel?
Adapalene gel is sold over the counter, so you do not need a prescription.
Is there a cheaper way to buy Adapalene gel?
Compare Cost Plus Drugs with a discount coupon such as GoodRx at a local pharmacy, since prices differ by pharmacy and ZIP code. Ask the pharmacy for its cash price in writing before you pay.
Does Pymander charge extra for Adapalene gel?
No. The prices on this page are the outside source’s own prices. Pymander adds no fee or markup.